Mutation frequency induced by different polymerases

Range Table - link
Organism Bacteria Escherichia coli
Reference Ji JP, Loeb LA. Fidelity of HIV-1 reverse transcriptase copying RNA in vitro. Biochemistry. 1992 Feb 4 31(4):954-8. p.957 table 1PubMed ID1370910
Method "[Researchers] present an assay for measuring the fidelity of reverse transcription. The assay detects a wide spectrum of mutations in a portion of the lacZa gene." See note beneath table
Comments "The mutation frequencies resulting from reverse transcription or DNA polymerization are compared in Table I. Copying DNA, the most error-prone enzyme tested was HIV-1 RT, with an error rate of about 1 in 5900 nucleotides polymerized."
Entered by Uri M
ID 110134