Lateral and longitudinal bond energies in an MT (microtubule) structure

Range lateral bond energy -2.2 to -5.7kT longitudinal bond energy -6.8 to -9.4kT kT
Organism Eukaryotes
Reference Tuszynski JA, Luchko T, Portet S, Dixon JM. Anisotropic elastic properties of microtubules. Eur Phys J E Soft Matter. 2005 May17(1):29-35. p.31 left column 2nd paragraphPubMed ID15864724
Primary Source VanBuren V, Odde DJ, Cassimeris L. Estimates of lateral and longitudinal bond energies within the microtubule lattice. Proc Natl Acad Sci U S A. 2002 Apr 30 99(9):6035-40.PubMed ID11983898
Method (Primary source abstract:) "[Researchers] developed a stochastic model of microtubule (MT) assembly dynamics that estimates tubulin-tubulin bond energies, mechanical energy stored in the lattice dimers, and the size of the tubulin-GTP cap at MT tips."
Comments "In fact, a recent paper by VanBuren et al. [primary source] estimated the values of lateral and longitudinal bond energies in an MT (microtubule) structure using a stochastic model of assembly dynamics. Their analysis predicts the lateral bond energy to be in the range from -2.2 to -5.7kT (which translates to -9.1?10^-21 to -2.4?10^-20J) while the longitudinal bond energy is given from -6.8 to -9.4kT (-2.8?10^-20 to -3.9?10^-20J)."
Entered by Uri M
ID 110107