Rate of turnover of whole skeleton

Range ~10 Table - link %/year
Organism Human Homo sapiens
Reference Manolagas SC. Birth and death of bone cells: basic regulatory mechanisms and implications for the pathogenesis and treatment of osteoporosis. Endocr Rev. 2000 Apr21(2):115-37. p.116 table 1 and p.122 right column bottom paragraphPubMed ID10782361
Primary Source (Source of table:) Parfitt AM 1994 Osteonal and hemi-osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone. J Cell Biochem 55 :273–286PubMed ID7962158
Method Note 'b' beneath table: "The 10% per year approximation for the entire skeleton is based on an average 4% turnover per year in cortical bone, which represents roughly 75% of the entire skeleton and an average 28% turnover per year in trabecular bone, which represents roughly 25% of the skeleton (0.75×4=3 and 0.25×28=7 3+7=10)."
Entered by Uri M
ID 109908