Estimated mutation density

Range Arabidopsis 1/300kb: rice & barley 1/Mb: soybean 1/550kb: pea 1/669 kb
Organism Plants
Reference Xin Z, Wang ML, Barkley NA, Burow G, Franks C, Pederson G, Burke J. Applying genotyping (TILLING) and phenotyping analyses to elucidate gene function in a chemically induced sorghum mutant population. BMC Plant Biol. 2008 Oct 14 8: 103. doi: 10.1186/1471-2229-8-103. p.10 left column bottom paragraphPubMed ID18854043
Primary Source 21. Greene EA, Codomo CA, Taylor NE, Henikoff JG, Till BJ, Reynolds SH, Enns LC, Burtner C, Johnson JE, Odden AR, et al.: Spectrum of chemically induced mutations from a large-scale reversegenetic screen in Arabidopsis. Genetics 2003, 164(2):731-740. & 22. Caldwell DG, McCallum N, Shaw P, Muehlbauer GJ, Marshall DF, Waugh R: A structured mutant population for forward and reverse genetics in barley (Hordeum vulgare L.). Plant J 2004, 40(1):143-150. & 41. Wu JL, Wu C, Lei C, Baraoidan M, Bordeos A, Madamba MR, Ramos- Pamplona M, Mauleon R, Portugal A, Ulat VJ, et al.: Chemical- and irradiation-induced mutants of indica rice IR64 for forward and reverse genetics. Plant Mol Biol 2005, 59(1):85-97. & 32. Cooper JL, Till BJ, Laport RG, Darlow MC, Kleffner JM, Jamai A, El- Mellouki T, Liu S, Ritchie R, Nielsen N, et al.: TILLING to detect induced mutations in soybean. BMC Plant Biol 2008, 8(1):9. & 31. Triques K, Sturbois B, Gallais S, Dalmais M, Chauvin S, Clepet C, Aubourg S, Rameau C, Caboche M, Bendahmane A: Characterization of Arabidopsis thaliana mismatch specific endonucleases: application to mutation discovery by TILLING in pea. Plant J 2007, 51(6):1116-1125.PubMed ID12807792, 15361148, 16217604, 18218134, 17651368
Comments "The estimated mutation density was lower than typically reported for Arabidopsis (1/300 kb) [primary source 21], slightly higher than barley [primary source 22] or rice (1/Mb) [primary source 41], but similar to the mutation density reported in soybean 1/550 kb [primary source 32] and pea 1/669 kb [primary source 31]."
Entered by Uri M
ID 109870