Fraction of charged tRNA under non-limiting amino acid supply

Range ~80 %
Organism Bacteria Escherichia coli
Reference Zhang G, Ignatova Z. Generic algorithm to predict the speed of translational elongation: implications for protein biogenesis. PLoS One. 2009 4(4):e5036. doi: 10.1371/journal.pone.0005036. p.2 right column top paragraphPubMed ID19343177
Primary Source Dittmar KA, Sørensen MA, Elf J, Ehrenberg M, Pan T. Selective charging of tRNA isoacceptors induced by amino-acid starvation. EMBO Rep. 2005 Feb6(2):151-7.PubMed ID15678157
Comments "The ribosomes are highly abundant in cells 18000 functional ribosomes exist, as shown for exponentially growing E. coli cell (CyberCell database), whereas the most abundant tRNA species are estimated to comprise only about 4700 copies per cell [BNID 108609 Table - link ] with approximately 80% charged fraction under non-limiting amino acid supply [primary source]."
Entered by Uri M
ID 109641