Wildtype 1.60: mutant 2.72 hours
||Budding yeast Saccharomyces cerevisiae
||Ramsey SA, Smith JJ, Orrell D, Marelli M, Petersen TW, de Atauri P, Bolouri H, Aitchison JD. Dual feedback loops in the GAL regulon suppress cellular heterogeneity in yeast. Nat Genet. 2006 Sep38(9):1082-7 p.1083 right column 2nd paragraphPubMed ID16936734
||"[Researchers] simulated and measured experimentally
the time courses of the reporter responses in
cells switched from noninducing medium
(raffinose) to galactose."
||"The fluorescence histograms from the
time-course experiment (Fig. 3) demonstrate
a transiently bimodal distribution of the
response in the double-loop-knockout and
a uniform rate of response in wild-type cells...[researchers] estimated the time scales for half of the
cells to respond as 1.60 h for the wild-type and 2.72 h for the mutant."