Numbers of DNA-binding transcription factors in five organisms

Range Table - link
Organism Various
Reference Babu MM, Luscombe NM, Aravind L, Gerstein M, Teichmann SA. Structure and evolution of transcriptional regulatory networks. Curr Opin Struct Biol. 2004 Jun14(3):283-91 p.286 table 1PubMed ID15193307
Comments “[Researchers] display estimates of the predicted transcription factors in five genomes in Table 1, ranging from about 300 in E. coli to over 3000 in humans. These constitute between 6% (in E. coli and yeast) and 8% (in human) of the encoded proteins in these organisms. van Nimwegen’s [ref 24 PMID 12957540] earlier observation that larger genomes tend to have more transcription factors per gene is in accordance with the trend seen in eukaryotes (Table 1).” See notes beneath table
Entered by Uri M
ID 109202