Diameter of hole in mitochondrial porin

Range 20 to 30 Å
Organism Bread mold Neurospora crassa
Reference Latorre R, Miller C. Conduction and selectivity in potassium channels. J Membr Biol. 1983 71(1-2):11-30. p.14 left column top paragraphPubMed ID6300405
Primary Source Marco Colombini, Pore size and properties of channels from mitochondria isolated from Neurospora crassa, The Journal of Membrane Biology 1980, Volume 53, Issue 2, pp 79-84
Comments "In the case of mitochondrial porin [primary source], the channel size estimated from the cutoff size for permeating molecules agrees well with the size calculated from the channel conductance, assuming that ions diffuse through a pore of cylindrical geometry, with a conductivity equal to that of the aqueous medium. These hole sizes are calculated to be quite large, 20-30 Å in diameter, and the transport rates are enormous, 10^8-10^9 ions per sec, at 100mV."
Entered by Uri M
ID 109167