Total zinc level within uninfected red blood cells

Value 1.1 fg/cell Range: ±0.1 fg/cell
Organism Human Homo sapiens
Reference Marvin RG et al., Fluxes in "free" and total zinc are essential for progression of intraerythrocytic stages of Plasmodium falciparum. Chem Biol. 2012 Jun 22 19(6):731-41. doi: 10.1016/j.chembiol.2012.04.013. p.732 right column bottom paragraphPubMed ID22726687
Method "[Researchers] apply submicron resolution X-ray fluorescence microprobe (XFM) microscopy, inductively coupled plasma mass spectrometry (ICP-MS), and zinc-specific fluorescent probes in order to interrogate, in a quantitative manner, the role of fluxes in essential metal ion concentrations within a single infected cell."
Comments "Total zinc levels within uninfected red blood cells (1.1 ± 0.1 fg) doubled in the infected cell (2.3 ± 0.5 fg), consistent with previously reported values for the same type of mixed-stage infected cells (Ginsburg et al., 1986)."
Entered by Uri M
ID 108837