| Comments |
"Two patterns of
FasL expression on carcinoma cells have been shown
by immunohistochemical staining: (1) up-regulation of
FasL expression on carcinoma is positively associated
with clinicopathological features in patients, shown by
that FasL expression is an early event in epithelial cell
transformation (adenoma), followed by an increase in
the percentage of FasL-expressing carcinoma cells in
high-stage or -grade lesions, and the poorer survival of
patients with high levels of FasL expression (Table 2)
and (2) high levels of FasL expression have been seen
as an independent factor for clinicopathological features,
indicated by the positive staining of persistent
FasL expression regardless of tumor stage, histologic
grade, invasion and metastasis in many studies." |