Contour length of DNA

Range ~1.5 mm
Organism Bacteria Escherichia coli
Reference Bakshi S, Siryaporn A, Goulian M, Weisshaar JC. Superresolution imaging of ribosomes and RNA polymerase in live Escherichia coli cells. Mol Microbiol. 2012 Jul85(1):21-38. doi: 10.1111/j.1365-2958.2012.08081.x. p.21 right column top paragraphPubMed ID22624875
Comments P.21 right column top paragraph: "The nucleoid does not fill the entire cytoplasmic volume, in spite of severe compaction of ~1.5mm of DNA contour length within a 3mm long × 1mm diameter cell." See Mondal et al., 2011 PMID 21641305 p.2605 right column bottom paragraph:"The 4.6 Mbp circular E. coli chromosome (ref 21) has a contour length of 1.6 mm, which is much larger than the rod-shaped cell dimensions of 2–4 µm in length and 0.5 µm in radius ( Fig. 1A)." See Gorle et al., 2017 PMID 28232991 p.677 left column 2nd paragraph: "In Escherichia coli (E. coli), chromosomal DNA has a contour length approximately 1000-fold larger than the ∼1 μm cell width, forcing it to adopt a compact super-coiled structure within the cell cavity [refs 1–3]."
Entered by Uri M
ID 108589