Differences between the folding free energies in vivo and in vitro for cellular retinoic acid binding protein (CRABP)

Value 2.2 kcal/mol Range: ±0.1 kcal/mol
Organism Unspecified
Reference McGuffee SR, Elcock AH. Diffusion, crowding & protein stability in a dynamic molecular model of the bacterial cytoplasm. PLoS Comput Biol. 2010 Mar 5 6(3):e1000694. p.7 left column 2nd paragraphPubMed ID20221255
Comments "...the differences between the folding free energies in vivo and in vitro are computed to be ... +2.2±0.1 kcal/mol for...CRABP... (blue bars in Figure 4A), with the positive signs indicating that the folding free energies of ... protein are calculated to be more favorable in vivo than in vitro."
Entered by Uri M
ID 108469