Osmolality at which growth ceases when grown on glucose minimal medium

Range ~1.6 to 2.0 Osm
Organism Bacteria Escherichia coli
Reference Cayley S, Record MT Jr. Large changes in cytoplasmic biopolymer concentration with osmolality indicate that macromolecular crowding may regulate protein-DNA interactions and growth rate in osmotically stressed Escherichia coli K-12. J Mol Recognit. 2004 Sep-Oct17(5):488-96. p.489 right column 3rd paragraphPubMed ID15362109
Primary Source McLaggan D, Logan TM, Lynn DG, Epstein W. Involvement of gamma-glutamyl peptides in osmoadaptation of Escherichia coli. J Bacteriol. 1990 Jul172(7):3631-6. AND Cayley S, Record MT Jr. Roles of cytoplasmic osmolytes, water, and crowding in the response of Escherichia coli to osmotic stress: biophysical basis of osmoprotection by glycine betaine. Biochemistry. 2003 Nov 4 42(43):12596-609PubMed ID1972940, 14580206
Comments "For E. coli K-12 grown in glucose minimal medium above 0.3–0.5 Osm, growth rate decreases approximately linearly with increasing osmolality and growth ceases at 1.6–2 Osm (primary sources)"
Entered by Uri M
ID 108394