Mean abundance of mRNA

Value 0.04 copies/cell
Organism Bacteria Mycoplasma pneumoniae
Reference Maier T, Schmidt A, Güell M, Kühner S, Gavin AC, Aebersold R, Serrano L. Quantification of mRNA and protein and integration with protein turnover in a bacterium. Mol Syst Biol. 2011 Jul 19 7: 511. doi: 10.1038/msb.2011.38. p.5 left column bottom paragraphPubMed ID21772259
Method P.5 left column bottom paragraph: "[Researchers] quantified individual average mRNA amounts per cell by spiking known amounts of reference RNAs into mRNA samples analysed by tiling arrays (Supplementary Figure S10)."
Comments P.5 left column bottom paragraph: "In agreement with findings in E. coli (Taniguchi et al, 2010) and previous estimates for M. pneumoniae (Weiner, 2003) measured mRNA abundances were on average below one copy per cell (mean abundance: 0.04)."
Entered by Uri M
ID 108348