Concentration of ribosomes in a eukaryotic cell

Range ~1 μM
Organism Eukaryotes
Reference Rospert S, Dubaquié Y, Gautschi M. Nascent-polypeptide-associated complex. Cell Mol Life Sci. 2002 Oct59(10):1632-9 p.1635 right column bottom paragraphPubMed ID12475173
Method (Based on 30µm diameter spherical cell and 6e+6ribosomes/cell:)(4p(15µm)^3/3)10^-15litres/µm^3.>>14137e-15litres/cell. (6e+6ribosomes/cell)/6e+23ribosomes/mole=1e-17moles/cell.>> 1e-17(moles/cell)/14137e-15litres/cell=~7e-7moles/litres~1e-6M=1µM
Comments "Assuming the number of ribosomes per cell to be roughly 6?10^6 [BNID 108290] and an average cell diameter of 30µm, the concentration of ribosomes in a eukaryotic cell is ~1 µM."
Entered by Uri M
ID 108291