Experimentally inferred neutral mutation rate

Range 3.46х10^-9 1/bp/generation
Organism Drosophila spp.
Reference Obbard DJ, Maclennan J, Kim KW, Rambaut A, O'Grady PM, Jiggins FM. Estimating Divergence Dates and Substitution Rates in the Drosophila Phylogeny. Mol Biol Evol. 2012 Aug 11.PubMed ID22683811
Primary Source Keightley PD, Trivedi U, Thomson M, Oliver F, Kumar S, Blaxter ML. Analysis of the genome sequences of three Drosophila melanogaster spontaneous mutation accumulation lines. Genome Res. 2009 Jul19(7):1195-201PubMed ID19439516
Comments Researchers estimated sequence divergence times across the 12 Drosophila genomes using the experimentally inferred neutral mutation rate of 3.46?10^-9 bp^-1 gen^-1 from D. melanogaster (primary source), converted to a time-based estimate of 0.0346 bp^-1 My^-1 by assuming 10 generations per year (e.g., Cutter 2008).
Entered by Uri M
ID 108233