Genome-wide recombination rate

Value 22.8 events/cell Range: ±0.4 events/cell
Organism Human Homo sapiens
Reference Jianbin Wang, H. Christina Fan, Barry Behr and Stephen R. Quake Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm, Cell 150, 402–412, July 20, 2012 p.403 right column bottom paragraphPubMed ID22817899
Method p.403 left column 2nd paragraph: "[Researchers] collected a sperm sample from a 40-year-old Caucasian individual (P0) whose genome has been sequenced (Pushkarev et al., 2009), clinically annotated (Ashley et al., 2010), and haplotype phased (Fan et al., 2011)."
Comments P.403 right column bottom paragraph: "At a genome-wide scale, the recombination rate of 22.8±0.4 SE (±3.7 SD) events per cell agrees well with the average male results implied from other methods, such as cytological imaging (49.8±0.4 SE [±4.3 SD] MLH1 loci within the tetraploid spermatocytes [Sun et al., 2004] and data inference (24.0±0.2 SE [±2.7 SD] from Caucasian pedigrees [Cheung et al., 2007])."
Entered by Uri M
ID 108035