Contribution of major oxygen-consuming processes to oxygen consumption rate of rat tissues in standard state

Range Table - link %
Organism Rat Rattus norvegicus
Reference Rolfe DF, Brown GC. Cellular energy utilization and molecular origin of standard metabolic rate in mammals. Physiol Rev. 1997 Jul77(3):731-58. p.739 table 2PubMed ID9234964
Primary Source See pointers to refs beneath table
Comments "Data for protein synthesis are calculated using data for whole body protein turnover and fractional contribution of each tissue to this figure (210) and assuming that the average molecular weight of a peptide bond is 110, ATP peptide bond stoichiometry is 4, and ATP/O is 2.5. Data for Na+-K+-ATPase and Ca2+-ATPase are from Clausen et al. (53). Data for substrate cycling are from Rabkin and Blum (169). Data for glucose and urea synthesis are from Kusaka and Ui (132), Berry et al. (14), and Haussinger et al. (100). Estimates of contribution of actinomyosin ATPase activity to ATP turnover are from data of Challoner (48), Suga (200), and Clausen et al. (53). Note that, where it was necessary to assume a value for P/O to calculate data presented here, a figure of 2.5 has been used. Data for rat tissue oxygen consumption rates in the resting state are taken from Table 1. Note also that because data used to compile this table are taken from different sources the sum of energy-requiring processes in some organs may exceed 100%. (Numbers in parentheses point to refs)"
Entered by Uri M
ID 107962