| Range |
3 to 4 enterocytes, goblet cells and enteroendocrine: ~21 Paneth cells Days
|
| Organism |
Human Homo sapiens |
| Reference |
Li HJ, Ray SK, Singh NK, Johnston B, Leiter AB. Basic helix-loop-helix transcription factors and enteroendocrine cell differentiation. Diabetes Obes Metab. 2011 Oct13 Suppl 1:5-12. doi: 10.1111/j.1463-1326.2011.01438.x. p.6 left column 2nd paragraphPubMed ID21824251
|
| Primary Source |
Cheng H, Leblond CP. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types. Am J Anat. 1974 Dec141(4):537-61.PubMed ID4440635
|
| Method |
Cell
labelling kinetics |
| Comments |
"Cell
labelling kinetics indicated that enterocytes, goblet cells and
enteroendocrine cells differentiated as cells migrate up the
crypt–villus axis turning over every 3–4 days, whereas Paneth
cells migrated downwards to the crypt base with a much
slower turnover of approximately 21 days (primary source)." |
| Entered by |
Uri M |
| ID |
107812 |