Percentage of promoter regions that contain multiple transcription start sites (TSSs)

Range ~35 %
Organism Bacteria Escherichia coli
Reference Cho BK et al., The transcription unit architecture of the Escherichia coli genome. Nat Biotechnol. 2009 Nov27(11):1043-9. p.1048 right column 3rd paragraph and p.1047 fig.4CPubMed ID19881496
Method Researchers describe a four-step systems approach that iteratively integrates multiple genome-scale measurements on the basis of genetic information flow to identify the organizational elements and map them onto the genome sequence
Comments Researchers observed that ~35% of promoter regions contain multiple TSSs representing an increase of >380% over current knowledge.
Entered by Uri M
ID 107774