Flux of water through an open MscL channel

Range ~4 H2O/nanosecond
Organism Unspecified
Reference Haswell ES, Phillips R, Rees DC. Mechanosensitive channels: what can they do and how do they do it? Structure. 2011 Oct 12 19(10):1356-69. p.1358 right column bottom paragraphPubMed ID22000509
Primary Source Louhivuori M, Risselada HJ, van der Giessen E, Marrink SJ. Release of content through mechano-sensitive gates in pressurized liposomes. Proc Natl Acad Sci U S A. 2010 Nov 16 107(46):19856-60.PubMed ID21041677
Comments MscL=Mechanosensitive channel of Large conductance. a flux of ~4 waters per ns through an open MscL channel was indicated in the computational studies of (primary source) which was sufficient to relax an osmotically stressed liposome in microseconds.
Entered by Uri M
ID 107629