Free level of Ca2+ in rod cells in darkness

Range ~0.5 μM
Organism vertebrates
Reference Baylor D. How photons start vision. Proc Natl Acad Sci U S A. 1996 Jan 23 93(2):560-5. p.562 right column 2nd paragraphPubMed ID8570595
Primary Source Lagnado L, Cervetto L, McNaughton PA. Calcium homeostasis in the outer segments of retinal rods from the tiger salamander. J Physiol. 1992 Sep455: 111-42 AND Gray-Keller MP, Detwiler PB. The calcium feedback signal in the phototransduction cascade of vertebrate rods. Neuron. 1994 Oct13(4):849-61. AND McCarthy ST, Younger JP, Owen WG. Free calcium concentrations in bullfrog rods determined in the presence of multiple forms of Fura-2. Biophys J. 1994 Nov67(5):2076-89.PubMed ID1282928, 7524559, 7858145
Comments Although the Ca2+ concentration in rod outer segments has proved difficult to measure, the free level in darkness is thought to be roughly 0.5µM (primary sources)
Entered by Uri M
ID 107394