Hydrophobic semithickness of bilayer regions of natural membranes and dioleoylphosphatidylcholine (DOPC)

Range 15Å Natural membranes: 14.8Å DOPC Å
Organism Generic
Reference Lomize AL, Pogozheva ID, Mosberg HI. Anisotropic solvent model of the lipid bilayer. 2. Energetics of insertion of small molecules, peptides, and proteins in membranes. J Chem Inf Model. 2011 Apr 25 51(4):930-46 p.939 left column 3rd paragraphPubMed ID21438606
Comments Dimensions of different bilayer regions in natural membranes and DOPC are rather similar: they have hydrophobic semithicknesses of 15 and 14.8 Å, respectively, with semiwidths of the central nonpolar region (z0) of 9 Å and 8.6, respectively, and widths of the “mid-polar” region of 6 and 6.2 Å, respectively (Supporting Information Table S4). The fitting shows that water concentration in outer bacterial membranes may be higher than in inner membranes (5.33 M in the “mid-polar” region and 0.55 M in the central region).
Entered by Uri M
ID 107251