Number of synapses/neuron at different neuronal densities in vitro

Range <500 neurons/mm^2 387.7±144.6 synapses/neuron: 500–4500 neurons/mm^2 157.1±69.0 synapses/neuron synapses/neuron
Organism Rat Rattus norvegicus
Reference Cullen DK, Gilroy ME, Irons HR, Laplaca MC. Synapse-to-neuron ratio is inversely related to neuronal density in mature neuronal cultures. Brain Res. 2010 Nov 4 1359: 44-55 p.49 left column bottom paragraphPubMed ID20800585
Method Cerebral cortical neurons were plated in planar culture at densities ranging from 10 to 5000 neurons/mm^2 and neuronal and synaptic densities were evaluated over 21 DIV (days in vitro).
Comments Note- PMID 19239892 p.738 left column bottom paragraph gives up to ~1,000 synapses per neuron
Entered by Uri M
ID 106651