Resting membrane potential of motor neuron

Value 65 mV
Organism Mouse Mus musculus
Reference Meehan CF, Moldovan M, Marklund SL, Graffmo KS, Nielsen JB, Hultborn H. Intrinsic properties of lumbar motor neurones in the adult G127insTGGG superoxide dismutase-1 mutant mouse in vivo: evidence for increased persistent inward currents. Acta Physiol (Oxf). 2010 Dec200(4):361-76 p.365 table 1PubMed ID20874803
Method "The intrinsic properties of spinal motor neurones were recorded in vivo under anaesthesia in presymptomatic G127X mice and in the WT controls."
Comments "Table 1 shows mean values for the basic intrinsic properties measured for the WT and G127X mutants. Due to [investigators’] selection criteria being a membrane potential of =-50 mV [they] cannot be certain that there were no differences in membrane potentials in general between WT and G127X motor neurons: however, in the population selected for analysis (i.e. meeting the criteria), there was no significant difference between the mean resting membrane potentials of motor neurons from WT and G127X mice." Exact value given in table is -65.18±7.24mV (n=33)
Entered by Uri M
ID 106527