Method |
"[Investigators] measured the levels of a series of metabolites possibly
related to the Pasteur effect in cultures which showed the effect
and compared them with those measured in cultures that did
not show it. A group of metabolites was formed by glycolytic
intermediates (Table 2) and other by metabolites that have been
implicated as possible regulators in the Pasteur effect (Table 3).
Included in this latter group are fructose 2,6-bisphosphate and
2-oxoglutarate, this last compound being the product of an
enzyme potentially implicated in the Pasteur effect [4]." |