In vivo cytoplasm viscosity

Value <=2 Centipoise
Organism Unspecified
Reference Ando T, Skolnick J. Crowding and hydrodynamic interactions likely dominate in vivo macromolecular motion. Proc Natl Acad Sci U S A. 2010 Oct 26 107(43):18457-62 p.18461 left column top paragraphPubMed ID20937902
Primary Source Luby-Phelps K. Cytoarchitecture and physical properties of cytoplasm: volume, viscosity, diffusion, intracellular surface area. Int Rev Cytol. 2000 192: 189-221. AND Ridgway D, et al., Coarse-grained molecular simulation of diffusion and reaction kinetics in a crowded virtual cytoplasm.Biophys J. 2008 May 15 94(10):3748-59 AND Verkman AS. Solute and macromolecule diffusion in cellular aqueous compartments. Trends Biochem Sci. 2002 Jan27(1):27-33.PubMed ID10553280, 18234819, 11796221
Comments "In [investigators’] simulations, the viscosity of the cytoplasm equals the value in water. The in vivo cytoplasm viscosity has been measured and is not significantly larger than bulk water, i.e., it is less than 2 centipoise (primary sources)." See BNID 102561, 103392, 101825
Entered by Uri M
ID 105903