| Value |
216.043
unitless
|
| Organism |
Generic |
| Reference |
Mann M, Ong SE, Grønborg M, Steen H, Jensen ON, Pandey A. Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome. Trends Biotechnol. 2002 Jun20(6):261-8. p.265 left column top sentencePubMed ID12007495
|
| Primary Source |
Steen H, Küster B, Mann M. Quadrupole time-of-flight versus triple-quadrupole mass spectrometry for the determination of phosphopeptides by precursor ion scanning. J Mass Spectrom. 2001 Jul36(7):782-90. AND Steen H, Küster B, Fernandez M, Pandey A, Mann M. Detection of tyrosine phosphorylated peptides by precursor ion scanning quadrupole TOF mass spectrometry in positive ion mode. Anal Chem. 2001 Apr 1 73(7):1440-8.PubMed ID11473401, 11321292
|
| Method |
A precursor-ion scanning method that can be
performed in the positive mode has recently
been developed for the specific detection of phosphotyrosine-containing peptides [primary sources]. This
method is based on the ability to selectively detect the
immonium ions of phosphotyrosine residues that
have an m/z value of 216.043. Immonium ions are
generated by double cleavage of the peptide backbone. |
| Entered by |
Uri M |
| ID |
105738 |