Percent of total glucose metabolized that is converted to gluconate with glucose as sole carbon source at 35°C and pH<6.5

Value 80 %
Organism Bacteria Klebsiella pneumoniae
Reference Hommes RW, Postma PW, Tempest DW, Neijssel OM. The influence of the culture pH value on the direct glucose oxidative pathway in Klebsiella pneumoniae NCTC 418. Arch Microbiol. 1989 151(3):261-7 p. 263 left column bottom paragraphPubMed ID2650650
Method "[Researchers] investigated the effect of the pH value of the growth environment on the activity and synthesis of the glucose dehydrogenase and the gluconate dehydrogenase in K. pneumoniae." "Klebsiella pneumoniae was grown under conditions of potassium limitation at D = 0.3 h-1 (doubling time 2.3hours) and at pH 6.0 using glucose as carbon and energy source."
Comments "The most striking result was an enormous production of gluconate and 2-ketogluconate by the chemostat cultures growing at pH values lower than pH 6.5, where about 80% of the total glucose metabolized was converted into gluconic and 2-ketogluconic acids."
Entered by Uri M
ID 105659