| Comments |
Abstract: "One-third of the 4,225 protein-coding genes of Escherichia coli K-12 remain functionally unannotated (orphans). Many map to distant clades such as Archaea, suggesting involvement in basic prokaryotic traits, whereas others appear restricted to E. coli, including pathogenic strains." P.930 right column top paragraph: "To
evaluate the degree to which the physiological functions of the 4,225 putative protein-coding sequences of
E. coli K-12 are characterized presently, [researchers] examined the scope of literature reference records curated in the UniProt annotation system
[ref 23 PMID 14681372]." For total Gene number of 4606 see BNID 100272. For 4,285 proteins see PMID 15911532 p.1205 right column top paragraph |