Number of different proteins in the brain synapse

Value 1000 Unitless
Organism Human Homo sapiens
Reference Grant SG. The synapse proteome and phosphoproteome: a new paradigm for synapse biology. Biochem Soc Trans. 2006 Feb34(Pt 1):59-63PubMed ID16417483
Comments Review article. Synapse proteomics has recently resulted in a quantum leap in knowledge of the protein composition of brain synapses and its phosphorylation. See O'rourke et al., 2012 PMID 22573027 p.366 box 1 4th paragraph:"Over 1,000 different protein isoforms from several major families of adhesion proteins are thought to span the synaptic cleft [refs 80–85 therein]. Therefore, the adhesion proteins contribute greatly to synaptic complexity."
Entered by Uri M
ID 104523