mRNA half-lives of Escherichia coli genes in degradosome mutant strains

Range Table - link
Organism Bacteria Escherichia coli
Reference Bernstein JA, Lin PH, Cohen SN, Lin-Chao S. Global analysis of Escherichia coli RNA degradosome function using DNA microarrays. Proc Natl Acad Sci U S A. 2004 Mar 2 101(9):2758-63PubMed ID14981237
Method To investigate the degradosome's proposed role as an RNA decay machine, researchers used DNA microarrays to globally assess alterations in the steady-state abundance and decay of 4,289 E. coli mRNAs at single-gene resolution in bacteria carrying mutations in the degradosome constituents RNase E, polynucleotide phosphorylase, RhlB helicase, and enolase.
Entered by Uri M
ID 104322