Diffusion coefficient of BSA in cytoplasm of fibroblast

Value 1 µm^2/sec
Organism Human Homo sapiens
Reference Peters R. Nucleo-cytoplasmic flux and intracellular mobility in single hepatocytes measured by fluorescence microphotolysis. EMBO J. 1984 Aug3(8):1831-6PubMed ID6207019
Primary Source Novikoff,A.B. and Holtzman,E. (1976) Cells and Organelles, 2nd edition, published by Holt, Rinehardt and Winston, NY.
Comments The diffusion coefficient of bovine serum albumin (BSA) was restricted more extensively in the cytoplasm of human fibroblasts amounting to 1×10^-8 cm^2/s as compared with 68×10^-8 cm^2/s in free solution (Wojcieszyn et al., 1981, PMID: 6945591). See BNID 104034 for D of BSA in water=64-72 µm^2/sec
Entered by Uri M
ID 104263