Median estimated half life of mRNA of hepatoma cells

Value 10 hours
Organism Human Homo sapiens
Reference Sharova LV, Sharov AA, Nedorezov T, Piao Y, Shaik N, Ko MS. Database for mRNA half-life of 19 977 genes obtained by DNA microarray analysis of pluripotent and differentiating mouse embryonic stem cells. DNA Res. 2009 Feb16(1):45-58.PubMed ID19001483
Primary Source Yang E, van Nimwegen E, Zavolan M, Rajewsky N, Schroeder M, Magnasco M, Darnell JE Jr. Decay rates of human mRNAs: correlation with functional characteristics and sequence attributes. Genome Res. 2003 Aug13(8):1863-72PubMed ID12902380
Method mRNA decay rates were measured in two human cell lines with high-density oligonucleotide arrays that enable the measurement of decay rates simultaneously for thousands of mRNA species.
Entered by Uri M
ID 104217