Median half life of mRNA of mouse embryonic stem cell

Value 7.1 hours
Organism Mammalian tissue culture cell
Reference Sharova LV, Sharov AA, Nedorezov T, Piao Y, Shaik N, Ko MS. Database for mRNA half-life of 19 977 genes obtained by DNA microarray analysis of pluripotent and differentiating mouse embryonic stem cells. DNA Res. 2009 Feb16(1):45-58.PubMed ID19001483
Method Researchers successfully obtained the rate of mRNA decay for 19 977 non-redundant genes by microarray analysis of RNA samples obtained from mouse embryonic stem (ES) cells.
Comments Median estimated half-life was 7.1 h and only <100 genes, including Prdm1, Myc, Gadd45 g, Foxa2, Hes5 and Trib1, showed half-life less than 1 h.
Entered by Uri M
ID 104215