Processivity of DNA polymerase I

Range 10-50 nucleotides
Organism Bacteria Escherichia coli
Reference Kelman Z, O'Donnell M. DNA polymerase III holoenzyme: structure and function of a chromosomal replicating machine. Annu Rev Biochem. 1995 64:171-200PubMed ID7574479
Primary Source Studwell PS, O'Donnell M. Processive replication is contingent on the exonuclease subunit of DNA polymerase III holoenzyme. J Biol Chem. 1990 Jan 15265(2):1171-8PubMed ID2153103
Comments Pol I dissociates rapidly from DNA, extending a primer only 10-50 nucleotides for each template-binding event
Entered by Uri M
ID 104121