Half life of B cells that undergo positive selection

Range 3-8 weeks
Organism Vertebrates
Reference Kenneth M. Murphy, Paul Travers, Mark Walport, Janeway's Immunobiology, 7th edition 2008 Garland Science pp.304
Comments Naive B cells are produced in bone marrow and then migrate to the periphery where they enter secondary lymphoid tissues. Those that successfully enter lymphoid follicles are said to undergo positive selection and recirculate 3-8 weeks
Entered by Uri M
ID 103583