Number of protein/cell in exponential phase on glucose medium, mass doubling time of 40 min

Value 2.35e+6 Copies/cell Range: Table- link Copies/cell
Organism Bacteria Escherichia coli
Reference Frederick C. Neidhardt AND H. Edwin Umbarger, Chemical Composition of Escherichia coli, chapter 3 in Neidhardt F.C. Escherichia coli and Salmonella: Cellular and Molecular Biology. 2nd edition. Vol 1. American Society of Microbiology (ASM) Press 1996. p.2 table 1
Primary Source [10] Neidhardt, F. C., J. L. Ingraham, and M. Schaechter 1990. Physiology of the Bacterial Cell: a Molecular Approach. Sinauer Associates, Sunderland, Mass. [11] Powell EO. Growth rate and generation time of bacteria, with special reference to continuous culture. J Gen Microbiol. 1956 Dec15(3):492-511. DOI: 10.1099/00221287-15-3-492PubMed ID13385433
Method Note 'a' under table link: "Calculated for an average cell in a population of E. coli B/r in balanced growth at 37°C in aerobic glucose minimal medium with a mass doubling time of 40 min. The cell is defined by dividing the total biomass, or the amount of any of its measured components, by the total number of cells in the population. This average cell, therefore, is approximately 44% through its division cycle (see primary source 11 for the function describing the distribution of cell ages in an asynchronous, steady state population) and, assuming that increase in cell mass is exponential, is approximately 33% larger than when it was born. This table is modified from data in Table 1 of primary source 10."
Entered by Uri M
ID 102990