Time required for the diffusion of the transmitter across the synaptic gap

Value 1 µsec
Organism Squid
Reference Llinás R, Steinberg IZ, Walton K. Relationship between presynaptic calcium current and postsynaptic potential in squid giant synapse. Biophys J. 1981 Mar33(3):323-51. fig. 8aPubMed ID6261850
Method presynaptic voltage clamp, a microelectrode which measured the potential of the postsynaptic element in close proximity to the junction.
Comments approximately 1 µsec for a gap width of 200 Angstroms and a diffusion coefficient of 10^-6 cm^2/sec
Entered by Uri M
ID 102702