Length of siRNA

Range 21-23 nucleotides
Organism Human Homo sapiens
Reference Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature. 2001 May 24411(6836):494-8.PubMed ID11373684
Method Western blotting and immunofluorescence microscopy. The firefly (Pp-luc) and sea pansy (Rr-luc) luciferase reporter-gene plasmids
Comments RNAi is ATP dependent yet uncoupled from mRNA translation.
Entered by Uri M
ID 102484