Ratio between deamination rate of 5 methylcytosine and unmethylated cytosine

Value 3 unitless
Organism Human Homo sapiens
Reference Barnes DE, Lindahl T.Repair and genetic consequences of endogenous DNA base damage in mammalian cells.Annu Rev Genet. 200438:pp. 447PubMed ID15568983
Primary Source Lindahl T, Nyberg B.Heat-induced deamination of cytosine residues in deoxyribonucleic acid.Biochemistry. 1974 Jul 3013(16):3405-10PubMed ID4601435
Comments the rate of deamination of5-methylcytosine (5-meC) is threefold higher than that of unmethylated cytosine
Entered by Uri M
ID 102464