Intracellular diffusion coefficient for glucose transporter

Value 100 µm^2/sec
Organism African clawed frog Xenopus laevis
Reference Zeuthen T, Zeuthen E, Macaulay N. Water transport by GLUT2 expressed in Xenopus laevis oocytes. J Physiol. 2007 Mar 1 579(Pt 2):pp. 357 fig. 12PubMed ID17158169
Method Human GLUT2 was expressed in Xenopus laevis oocytes and incubated in Kulori medium
Comments This is one fifth of the value for free solution. The response to the methyl-glucose was calculated for three values of Di: 10–5, 10–6 and 10–7 cm2 s–1 without cotransport (continuous line) and with cotransport (dashed line 35 water molecules per methyl-glucose molecule). The best correspondence with measurements was obtained for a Di of 10–6 cm2 s–1.
Entered by Uri M
ID 102428