Life time of actin patches

Value 20 sec
Organism Fission yeast Schizosaccharomyces pombe
Reference Wu JQ, Pollard TD. Counting cytokinesis proteins globally and locally in fission yeast. Science. 2005 Oct 14 310(5746): p.312 right column bottom paragraphPubMed ID16224022
Primary Source Sirotkin V, Beltzner CC, Marchand JB, Pollard TD. Interactions of WASp, myosin-I, and verprolin with Arp2/3 complex during actin patch assembly in fission yeast. J Cell Biol. 2005 Aug 15 170(4):637-648.PubMed ID16087707
Method Primary source abstract: "[Researchers] used biochemical analysis and live cell imaging to investigate actin patch assembly in fission yeast Schizosaccharomyces pombe."
Comments "Actin patches concentrate at cell poles and at the cell-division site where the cell wall grows (Fig. 2B). The molecular composition of each patch varies over its 20-s lifetime (primary source) as it forms, matures, and dissociates (primary source & ref 25 PMID 14622601), so measurements on patches with random ages vary considerably (Fig. 2B and Table 1 standard deviations 38 to 62% of means)." Primary source abstract: "Yeast actin patches are dynamic structures that form at the sites of cell growth and are thought to play a role in endocytosis."
Entered by Uri M
ID 102266