Gibbs free energy change due to ATP hydrolysis in recovering muscle

Value -69 kJ/mol Range: ±2 Table - link kJ/mol
Organism Human Homo sapiens
Reference Wackerhage, H. et al. Recovery of free ADP, Pi, and free energy of ATP hydrolysis in human skeletal muscle. J Appl Physiol (85):2140-2145. 1998. p.2143 table 1PubMed ID9843537
Method 31P-NMR. (Nuclear Magnetic Resonance). (Ron Milo, Cell Biology by the Numbers:) "The natural form of phosphorus (31P) has magnetic properties, so there is no need to add any substance in order to obtain results from the spectrometer. The tissue such as muscle is placed in a strong magnetic field and shifts in frequency of radiofrequency pulses are used to infer concentration of ATP and Pi directly from the peaks on the NMR spectra." p.2141 right column 2nd paragraph: "?GATP is assumed to match the free energy of PCr (Phosphocreatine) hydrolysis."
Comments This measurement was performed 2-5 minutes after ischemia and exercise. This study was done on endurance-trained athletes. The change in free energy due to ATP hydrolysis of resting muscle in non-athletes is likely to have a slightly lower absolute value.
Entered by Phil Mongiovi
ID 101944