Nasal mucus volume

Value 3 mm^3
Organism Mouse Mus musculus
Reference Asahi et al, Protection against influenza virus infection in polymeric Ig receptor knockout mice immunized intranasally with adjuvant-combined vaccines. J Immunol. 2002 Mar 15 168(6):2930-8. p. 2932 right column table 1PubMed ID11884464
Method The mucus volume was estimated by assuming that the thickness of the mucus layer, including both the mucus blanket (4- to 8-µm thickness) and the periciliary space (cilia, 5–7 µm long), was 0.01 mm (refs 47, 48 in article). Table 1 shows that the surface area of the nasal cavity is ~300 mm^2 and the mucus volume is ~3mm^3 when the thickness of the mucus layer is 0.01 mm.
Comments The mucus volume that covers the surface of the nasal cavity was calculated by assuming that the thickness of the mucus blanket including periciliary space was 0.01 mm. Sum of mucosal volumes of Squamous cell epithelium (0.3mm^3), Columnar epithelium (1.5mm^3) and olfactory epithelium (1.2mm^3).
Entered by Ben Marks
ID 101564