Overall genome size

Value 3.08e+9 Base pairs
Organism Human Homo sapiens
Reference International Human Genome Sequencing Consortium. Finishing the euchromatic sequence of the human genome. Nature. 2004 Oct 21 431(7011):931-45. P.932 right columnPubMed ID15496913
Method P.931 right column bottom paragraph: "In total [researchers] generated a shotgun sequence from 59,208 large-insert clones (total length ~5.84 gigabases (Gb)) and finished the sequence from 45,742 of these clones (total length ~3.67 Gb). The clones consisted primarily of bacterial artificial chromosomes (BACs), but also included some P1-artificial chromosomes (PACs), yeast artificial chromosomes (YACs), fosmids and cosmids they carried DNA from multiple anonymous sources [ref 15]." P.932 left column bottom paragraph: "The human sequence reported here consists of 2,851,330,913 nucleotides, lying almost entirely within the euchromatic portion of the genome. It is interrupted by only 341 gaps, of which 33 gaps (totalling ~198 megabases (Mb)) reflect heterochromatin, which was not targeted by the Human Genome Project (HGP), and 308 gaps (totalling ~28 Mb) are euchromatic."
Comments P.932 right column: "The euchromatic genome is thus ~2.88 Gb and the overall human genome is ~3.08 Gb." See link for the "Golden path length" For Euchromatic genome see BNID 100396 Comment from JH: "Because the human genome size is about 3 billion, and cells contain a genome from mom and another from dad, human cells (except germ cells) contain about 6 billion base pairs."
Entered by Ron Milo - Admin
ID 101484