Number of nuclear pores per nucleus

Value 5058 pores/nucleus
Organism Mouse Mus musculus
Reference Maul GG, Deaven L. Quantitative determination of nuclear pore complexes in cycling cells with differing DNA content. J Cell Biol. 1977 Jun73(3):748-60. p.752 table IPubMed ID406262
Method P.753 right column 3rd paragraph: "[Investigators] decided to extend the number of different cell lines and select them according to different DNA content. Table I provides the summary of the data collected during this extended investigation, and reveals an obvious increase in nuclear surface with increasing DNA content: this increase is not proportional, however."
Comments P.751 right column 2nd paragraph: "The numbers in Table I represent the corrected values. Briefly, the indentation at the cytocenter results in a nuclear shape similar to the shape of an indented ball. Since most cells will appear round when the indentation is parallel to the optical axis, the volume will be extremely overestimated if the formula for a sphere is used."
Entered by Ben Marks
ID 101387