||Nematode Caenorhabditis briggsae
||Stein et al, The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics, PLoS Biol. 2003 Nov1(2):E45.PubMed ID14624247
||To sequence the C. briggsae genome, researchers adopted a hybrid strategy combining whole-genome shotgun sequencing (WGS) with a high-resolution, sequence-ready physical map. The previously finished clone-based sequence was then integrated with the whole-genome assembly to produce the draft sequence.
||Researchers estimate that 3% of the bases in the assembly consist of undetected overlaps. Combined with the estimated coverage of 98%, this yields an estimate for the C. briggsae genome size of 104 Mbp. However, this figure contains substantial uncertainty, in part because the finished sequence is not a random selection of the genome, and this number is certain to be revised as additional finishing is performed. 104,000,000 bp is slightly larger than the genome size of C. elegans, but the difference is primarily due to more repetitive sequence in C. briggsae. C. elegans and C. briggsae have the same chromosome number (six) and genome
sizes, and they occupy the same ecological niche.
||Ron Milo - Admin