||Fruit fly Drosophila melanogaster
||Adams MD et al, The genome sequence of Drosophila melanogaster. Science. 2000 Mar 24 287(5461):2185-95. abstract & p.285 right column bottom paragraphPubMed ID10731132
||Abstract: "[Researchers] have determined the nucleotide sequence of nearly all of the approximately 120-megabase euchromatic portion of the Drosophila genome using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map." P. 2194 middle column 2nd paragraph: "Genome assembly relied on the use of several types of data, including clone-based sequence,
whole-genome sequence from libraries
with three insert sizes [2 kb, 10 kb, and 130 kb], and a Bacterial Artificial Chromosome (BAC)-based sequence-tagged site (STS) content map. The combination of these resources resulted in a set of ordered contigs spanning nearly all of the euchromatic region on each chromosome arm."
||P.2185 right column bottom paragraph: "The Drosophila genome is ~180 Mb in size, a third of which is centric heterochromatin. The 120 Mb of euchromatin is on two large autosomes and the X chromosome. The small fourth chromosome contains only ~1 Mb of euchromatin. The heterochromatin consists mainly of short, simple sequence elements repeated for many megabases, occasionally interrupted by inserted transposable elements, and tandem arrays of ribosomal RNA genes."
||Ron Milo - Admin