RNA polymerase transcription rate of mRNA in different media and doubling times

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Range 28-89 Table - link nucleotides/sec
Organism Bacteria Escherichia coli
Reference Vogel U, Jensen KF. The RNA chain elongation rate in Escherichia coli depends on the growth rate. J Bacteriol. 1994 May176(10):2807-13PubMed ID7514589
Method The mRNA chain elongation rate was determined by the time lag between induction of transcription of specific mRNAs (lacZ, infB) and the appearance of specific hybridization to DNA probes from the 3' ends of the respective genes.
Comments Slowest rate 28 nts/sec on glucose-15 alpha-methyglucoside medium (doubling time 200 min) fastest rate 89 nts/sec on glucose casamino acid medium (doubling time 35 min)
Entered by Uri M
ID 104902